UEFA Europa League · League Stage - 3
1899 Hoffenheim vs Lyon prediction, team news and preview
Pointless 1899 Hoffenheim host Lyon, who have won both league-stage games, on Thursday 22 October 2026. Our preview weighs a leaky home side against a high-scoring visitor with several knee problems.
MATCH PULSE EditorialPublished 5 min read
At a glance
- Competition
- UEFA Europa League · League Stage - 3
- Kick-off (your time)
- Venue
- Prezero Arena
- Where to watch
- See below
1899 Hoffenheim vs Lyon: what the match decides
1899 Hoffenheim host Lyon at the Prezero Arena on Thursday 22 October 2026 in Matchday 3 of the Europa League league stage. The two sides sit at opposite ends of the 36-team table. Lyon are eighth with 6 points from two wins, level on points with leader Juventus, while Hoffenheim are 30th with no points and a goal difference of -3.
For Hoffenheim this is close to a must-not-lose game. Two defeats leave them well behind, and a third would make the rest of the league stage hard work. For Lyon, a third win would keep them in the top-eight conversation and in position to avoid the play-offs. Our lean is towards the visitors, though the head-to-head record suggests this fixture is rarely settled easily.
Hoffenheim and Lyon recent form
Hoffenheim have lost four of their last five games in all competitions (LLLLW), scoring 7 and conceding 12, or 1.4 for and 2.4 against per game. They have not kept a clean sheet in that run, and four of the five matches had both teams scoring. At home they have lost both games, 2-3 to Hamburger SV and 2-3 to Besiktas, conceding 3.0 per game at the Prezero Arena. The one recent success was a 2-1 win at Borussia Monchengladbach on 18 October.
Lyon's last five read WWLWW: four wins, one defeat, 12 goals scored and 6 conceded, which is 2.4 for and 1.2 against per game. They kept one clean sheet, a 4-0 win over Rennes, and every one of their five games produced more than 2.5 goals. Away from home the picture is more mixed: one win and one defeat from two, with 3 scored and 3 conceded. They won 2-1 at Anderlecht in this competition and lost 1-2 at Lens in Ligue 1.
Form
- 1899 Hoffenheim
- L
- L
- L
- L
- W
- Lyon
- W
- W
- L
- W
- W
Last five games, oldest first
1899 Hoffenheim vs Lyon team news
Hoffenheim have four players listed as out: N. De Cat (knee injury), A. Hajdari (foot injury), P. Wimmer (thigh injury) and L. Engelns, who is listed as off the roster. No doubtful players are reported in our data. With 12 goals conceded in five games, losing defensive options is a concern, though our facts do not say which positions these players usually fill.
Lyon are without three players, all listed as out: L. Openda (leg injury), M. Ouedraogo (knee injury) and N. Tagliafico (knee injury). No doubts are reported on their side either.
Line-ups have not been published in our data. They are confirmed about an hour before kick-off, and this preview reflects the absences known so far.
1899 Hoffenheim
- N. De CatKnee InjuryOut
- L. EngelnsOff the rosterOut
- A. HajdariFoot InjuryOut
- P. WimmerThigh InjuryOut
Lyon
- L. OpendaLeg InjuryOut
- M. OuedraogoKnee InjuryOut
- N. TagliaficoKnee InjuryOut
Storylines for Hoffenheim and Lyon
Hoffenheim's story is one of margins and defending. Their European defeats were 0-2 at OFI and 2-3 against Besiktas, and they have lost four of five overall. The 2-1 win at Gladbach on 18 October, only four days before this game, is the one result to build on, and it came away from home, where they have been more solid than at the Prezero Arena.
Lyon arrive with momentum. They beat Crystal Palace 3-2 and Nice 2-1 in the last week, so their recent wins have come with goals at both ends. They have scored five in two European games, with three conceded. A third straight win would keep them among the early pacesetters and ease pressure later in the league stage.
Where Hoffenheim vs Lyon will be decided
The main contrast is Hoffenheim's defence against Lyon's attack. Lyon average 2.4 goals per game across their last five, while Hoffenheim concede 2.4 and 3.0 at home. If those trends hold, Lyon should create enough chances to score at least twice.
The other side of it is more balanced. Hoffenheim have scored 2.0 per game at home and failed to score only once in their last five. Lyon concede 1.2 per game overall and 1.5 away, so Hoffenheim should find chances too. That points to an open game with goals at both ends, in line with the numbers: four of Hoffenheim's last five and all five of Lyon's went over 2.5 goals.
Hoffenheim vs Lyon head-to-head
The two clubs have met three times, and all three games were draws: 3-3 at Hoffenheim on 23 October 2018, 2-2 at Lyon on 7 November 2018 (both Champions League), and 2-2 in Hoffenheim on 7 November 2024 in the Europa League. Hoffenheim and Lyon have no wins against each other.
Those meetings averaged 4.67 goals per game, and both teams scored in all three, with more than 2.5 goals each time. It is a small sample, but it fits the open, high-scoring profile of both sides now.
1899 Hoffenheim vs Lyon prediction
Our lean is a narrow Lyon win. They have the stronger form (four wins in five against one for Hoffenheim), the better goal numbers (2.4 scored and 1.2 conceded per game against 1.4 and 2.4), and a clear table advantage. Hoffenheim's home record of two defeats and six goals conceded gives little reason to expect a tight defensive performance.
On goals, we lean towards over 2.5 and both teams scoring. Lyon's five games all passed 2.5 goals, Hoffenheim's home games average five goals in total, and all three previous meetings had both sides scoring. The draw cannot be ruled out given the head-to-head record, and an early Hoffenheim goal, or the injuries to Lyon's knee-affected players, could shift the balance. This is a lean, not a certainty.
MATCH PULSE's three AI engines (GPT, Claude and Gemini) publish their independent analysis of the match before kick-off.
How to watch 1899 Hoffenheim vs Lyon
No official broadcasters are listed in our data for this match. Check the UEFA Europa League's official broadcast partner in your country and its official app, which will show the match live.
The match is played on Thursday 22 October 2026 at the Prezero Arena. Kick-off time is displayed on this page in your local time zone.
We have not listed this competition's broadcasters yet. Check the competition's official broadcast partner in your country and its official app.
Only official rights holders are listed; availability can change. Watching through unofficial streams is unsafe and unfair to the clubs.
Frequently asked questions
When is 1899 Hoffenheim vs Lyon?
The match takes place on Thursday 22 October 2026 in Matchday 3 of the Europa League league stage. The kick-off time on this page is shown in your own time zone.
Where is Hoffenheim vs Lyon played?
The match is at the Prezero Arena, Hoffenheim's home ground.
What is the team news for Hoffenheim vs Lyon?
Hoffenheim are without N. De Cat, A. Hajdari, P. Wimmer and L. Engelns (off the roster). Lyon are missing L. Openda, M. Ouedraogo and N. Tagliafico. Line-ups are confirmed about an hour before kick-off.
What is the head-to-head record between Hoffenheim and Lyon?
They have met three times and all three games were draws (3-3, 2-2 and 2-2), averaging 4.67 goals per game.
Who is favoured in Hoffenheim vs Lyon?
Our lean is a narrow Lyon win with goals at both ends, based on their stronger form and Hoffenheim's home record. A draw remains a real possibility.
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